Maintenance of proteostasis is critical for neuronal functions, as the accumulation of misfolded or damaged proteins leads to neurodegeneration. Cooling is generally neuroprotective and is used in various clinical settings. However, how it impacts neuronal proteostasis remains unclear. In rodents, the neuroprotective effects of cold have been largely attributed to the cold-inducible protein RBM3. Here, […]
The Daurian ground squirrel (Spermophilus dauricus) is an important animal model that is frequently used by researchers studying the physiological ecology of hibernation in China. There has been considerable controversy regarding the classification of its subspecies, and there is a lack of relevant comparisons of morphometric data. To clarify this issue, this study aims to […]
The Arctic ground squirrel (AGS, Urocitellus parryii), an extreme hibernator, exhibits remarkable resilience to stressors like hypoxia and hypothermia, making it an ideal model for studying cellular metabolic adaptation. The underlying mechanisms of AGS resilience are largely unknown. Here, we use lipidomic and metabolomic profiling to discover specific downregulation of triglyceride lipids and upregulation of […]
Understanding the immunological profiles of wild bats is crucial for monitoring population health, disease dynamics, and stress responses in changing environments. Here, we present a dataset of 747 blood smear samples collected from 19 European bat species between 2017 and 2023 in Ukraine. For a substantial portion of individuals, red and white blood cell counts […]