Metabolic inflammation is an inflammation event that occurs during fattening driven by diet-induced changes to the microbiota leading to increased permeability of the gut barrier and infiltration of bacterial products. This triggers inflammation in the gut and distant tissues (i.e., white adipose [WAT]). We have previously shown that 13-lined ground squirrels (Ictidomys tridecemlineatus), obligate hibernators, […]
Memories leave lasting physical changes at the synaptic level. Although stable, larger spines are thought to support memory, the high turnover of dendritic spines and the drifting of neuronal representations after memory formation suggest alternative possibilities. To elucidate the structural trace underlying memory retention, we used a mouse model of artificial hibernation. During hibernation, hippocampal […]
CONCLUSION: Post-hibernation recovery in R. kukunoris involves cross-level parallel responses in host energy status, digestive system structure and gut microbiota. High- and low-altitude populations may adopt different physiological recovery strategies after hibernation, providing new evidence for understanding seasonal adaptation in amphibians inhabiting cold environments.
Hibernation is characterized by repeated torpor-arousal cycles during which profound physiological suppression occurs, but its effect on memory retention remains controversial. This may be partly due to the fact that most previous studies have focused on obligatory hibernators, often examining only single species, which can limit comparability between studies. We investigated whether facultative hibernation affects […]